What's Killing Bodybuilders And Other Athletes?

Preparation, Preparedness & Prevention Fitness and Nutrition
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Data starting to get published supporting my basic hypothesis, Oxidative stress via GSH depletion a key aspect of covid related pathogenesis and likley vaccine induced myocarditis, acute Pericarditis- Myopericarditis in young men:

Int J Gen Med. 2022; 15: 161–167.

The Evaluation of Oxidative Stress in the Young Adults with COVID-19 mRNA Vaccines Induced Acute Pericarditis- Myopericarditis

Abstract
Background

During COVID-19 pandemic, several vaccines have been developed such as mRNA vaccines. However, acute pericarditis and myocarditis/myopericarditis cases have been described after mRNA vaccination. The mechanism for the development of cardiac involvement is unknown. Potential mechanism for oxidative stress associated with vaccine-induced heart involvement is unidentified. This study aimed to examine the role of oxidative stress and the heart involvement in young adults vaccinated with COVID-19 mRNA vaccines.
Methods

In this cross-sectional study, a total of 23 participants were included and 10 of these participants were asymptomatic patients (control group). Comparison of the cardiac involvement and control group was made by using troponin I, C-reactive protein (hsCRP), D-dimer levels, and oxidative stress tests including nitric oxide, and imaging techniques (ECG, echocardiography, cardiovascular magnetic resonance).
Results

The median age of acute pericarditis group (10 patients) was 22 years (Q1-Q3: 18.5–31), and the mean age was 24.4±7.5 years. The median age of myopericarditis group (3 patients) was 22 years (Q1–Q3 18.0–25.0), and the mean age was 21.6 ±3.5 years. All the myopericarditis cases were male. The patients with myopericarditis had higher troponin I level, hsCRP, and D-dimer levels (troponin I level; 1600.00 ng/mL; D-dimer; 1.20 μg/mL, hsCRP; 3.0 mg/L, respectively; p < 0.05). Serum nitric oxide levels and OSI (total oxidant status, H2O2/total antioxidant status) were lower in myopericarditis group than the control and acute pericarditis group (p < 0.05). This shows inflammatory and procoagulant state.
Conclusion

Vaccine-induced myopericarditis cases are associated with oxidative stress test abnormality (abnormal NO, OSI levels). However, there is no relationship between NO levels and other oxidative stress tests difference in vaccine-induced acute pericarditis. It is thought that vaccine-induced pericarditis and myopericarditis could have different pathogenesis. This could make it necessary to reassess the second dose of vaccination for vaccine-induced cardiac involvement cases.

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I’m of the opinion that COVID infections as well as vaccination could contribute to this. My options were to vaccinate or face COVID without being vaccinated. Based on my experiences, I chose to get vaccinated. This was when the vaccines were 90%+ effective, prior to mutations that made them far less so. I got one booster, as Omicron was coming over, but have not pursued further vaccination, and won’t unless COVID cases kick up in greater numbers, and/or a more effective vaccine comes out for the strains involved. I chose Pfizer because of its efficacy being similar to Moderna, with a much lower effect on the recipient. I never considered J&J, as it was far less effective and had more side effects from the literature I read. I think people went with it because of cost/1 and done (interestingly, the 1 and done J&J was similarly effective to half the Prizer/Moderna series, so you COULD have just done that…), and because of fear of newer methods/mRNA vaccines.

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I cannot support this with hard data, but it’s been my experience that when you put people through a big routine change, they are more likely to die.

Staying home.
Working from home.
Outsourcing.
Lockdowns.
Going to the gym/buying a Peloton.
Not going to the gym.

It was a HUGE routine change for a lot of people, and that tends to kill.

Just my opinion/observation with no data to support it besides experience.

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In line and supportive of my OP and post, very important: Just released by the Joseph A. Ladapo, MD, PhD
FL Surgeon General:

“Today, we released an analysis on COVID-19 mRNA vaccines the public needs to be aware of. This analysis showed an increased risk of cardiac-related death among men 18-39”

Full report:

“The Florida Department of Health (Department) conducted an analysis through a self-controlled case
series, which is a technique originally developed to evaluate vaccine safety. This studied mortality risk
following mRNA COVID-19 vaccination. This analysis found there is an 84% increase in the relative
incidence of cardiac-related death among males 18-39 years old within 28 days following mRNA
vaccination. Individuals with preexisting cardiac conditions, such as myocarditis and pericarditis…”

https://floridahealthcovid19.gov/wp-content/uploads/2022/10/20221007-guidance-mrna-covid19-vaccines-doc.pdf

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That’s kindof my personal opinion, as well. With the decrease in efficacy against the new strains, the risk/reward is tilted in favor of “wait and see” for now, the way I read it. I am still very glad I got vaccinated back in 2020, though.

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That depends strictly on who you are. Older person with say various risk factors for serious complications, hospitalization, and death from covid, risk/benefit absolutely favors being vaccinated. A healthy male teen athlete? Not so much. That’s the issue that’s been raised by various pro vaccine docs (vids posted on this forum and linked …) that the one size fits all approach to the vaccines is BAD science. Now we have hard support for that reality, and it’s costing lives and top docs in their field - their lane - are pushing back and being attacked as “anti vax” and nothing could be further from the truth there.

For me, it made sense to be vaccinated as the risk/benefits clearly favored it in my case.

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Agreed.

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I just saw where Sara Lee, a young, fit, cute 30 year old WWE wrestler died. Eerie post that she had just gotten over the sniffles.

https://nypost.com/2022/10/07/wwe-star-sara-lees-eerie-social-media-post-before-tragic-death-at-30/

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Covid does worse things than the vaccine. Hence why I chose vaccination back in 2020 back when it was very effective and covid was worse

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If I were a 20-40 yearly old, there’s no way in hell I would’ve taken the vaccine. They’ve always been a low risk group. More data is supporting the risk from the mRNA shot, links to studies in the article.

https://redstate.com/bonchie/2022/10/08/florida-contradicts-the-cult-tells-younger-men-not-to-get-the-mrna-vaccines-n639770

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The vaccine has risks. Covid was worse. Its like trotting out studies showing bootcamp injuries and saying yoid rather deploy with no training.

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Risk/benefit wise, it’s not risk of vaccines vs no vaccines, it’s risks of vaccine vs exposure to covid minus being vaccinated. Everyone on this planet has been, or will be, exposed to covid. I’d also assume you didn’t check out the OP article for context.

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Obviously it’s climate change and/or global warming. Take your pick.

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What were your observations? Were you seeing vaccine patients come in with bumped trops and fibrinogen, etc? I just didn’t see it. I also noted most of my patients who did poorly were unvaccinated. The vaccinated ones typically were discharged home from the ER with minor/no symptoms, or were incidental positives just due to protocol testing for things like preop. Long story short, I just didn’t see even a fraction of the issues from vaccination as I did covid. Now that things have gone on another 18mo, I am seeing less efficicacy of vaccination, but still no issues. Our numbers are pretty low now, though. What have you seen at your facilities? Ive spent the last 12 years working ICU and ER, among other departments, and the last several years working the covid wards, in addition. While its only a sample of one person’s experience, I do feel that over this time, it’s been pretty straightforward. Id like to know what other professionals who work with these patients have observed with the labwork and outcomes, as well, and hope you’ll share more than a meme. We can all use data and experience to improve.

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My communications with med pros in the trenches, and that’s quite a few at this point, mirrors your experiences. The data generally supports your et al experiences. But, people who read an article on some web site that supports their fears and conformation bias, they know better…

Much of that does fall squarely on the horrible messaging and response of the NIH, CDC, etc who allowed themselves to get politicized and part of the pissing match between the orange guy and those with TDS, and I do understand how/why some just don’t trust the messaging afters seeing the cluster F that was the approach to covid.

Having said that, they’d be better off asking Qs of people like yourself and perhaps myself as to best practices, those they should follow for good balanced objective science/data based advice, etc vs posting a meme etc if they lack the sci/med background to parse through it all, which is challenging and close to a full time job.

As I said from day one, will say again:

• There’s no doubt at all vaccines were a benefit for certain populations and saved lives
• We will not vaccinate our way out of covid

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My family of 5, only 1 had 1 dose of Vaccination (male, 22yr).

We’ve all had the 'Rona 2-3 times. Symptoms ranged from sniffles to fever / cough for 24-36 hrs tops for the un-vaxed (1 healthcare worker, 2 other minors, 1 other adult); without tests, over 50% of the time you wouldn’t even consider yourself sick.

The one who got it the worst was vax’ed, fever for 2-3 days, fully recovered in 5.

Yeah, if you are morbidly obese, old, frail, etc the vax was likely a good call. But calling it a vax is a joke. It’s a crappy flu type shot that nobody wants anymore.

I believe in traditional vax’s that actually prevent you from getting the disease, not this bullshit. But of course healthy people dying from the vax is cool, because ‘it was for the greater good’.

F that noise.

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It’s ivory tower syndrome. People who are heading these organizations are so divorced from working with actual PEOPLE that they think “I have presented the data, now they will make the logical choice!” and when that obviously doesn’t happen, they completely melt down. Because they don’t know how the human animal works. Then it gets all sideways just like we saw.

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I wish you and yours well, Cheers!

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Understood. This thread was never intended as a general pro/con vax discussion thread, but a discussion and possible warning for a specific sub set population: young male athletes, and male BBer of any age. I have left all the general threads such as (1) as they have become an echo chamber and a waste of time in my view unless you enjoy echo chamber threads like that.

(1) https://www.m4carbine.net/showthread.php?234067-Is-the-Covid-narrative-falling-apart