I know it’s not really an answer to your question, but I’d say try to convince her to buy a G19 or S&W Shield or whatever. It’s a lot easier to learn to manipulate a compact auto than to shoot a small 38 well.
Otherwise…
I had a S&W 442, and a 2.5" 686+, and they were both really nicely made guns. The 686+ was a hell of a lot more enjoyable to shoot, obviously, and I could actually use it effectively. I would never carry a 442 or similar without lasergrips, and a larger grip. The boot grip is just too small; it would rotate in my hand with every shot. And the fixed sights were not very useful, they were hard to see and POI was nowhere near POA–though, that’s highly ammo dependent. Recoil was not fun at all. I’d much, much rather shoot factory 357 Magnum in the 686+ than factory 38 Special +P in the 442.
If you can find a shrouded ejector Detective Special for a decent price, they’re really nice little guns. It’d probably need a trigger job. I really liked the one I had (with a factory-bobbed hammer with the SA notch removed), the steel frame gave it enough weight to tame the recoil but it was still extremely easy to conceal, and you get 6 shots instead of the 5 in a J-frame. But, the guns aren’t built for high volume +P shooting.
I’ve never heard anything bad about SP101s. I don’t like their triggers, but I am very much a S&W revolver guy, and Rugers are just different. They’re overbuilt for the application, however. 5 ounces heavier than a Detective Special and a 5 shot gun, for reference. I have friends that like them, and Ruger revolvers are generally considered bulletproof.
The Ruger LCR and the S&W Bodyguard 38 seem fairly popular. I have only handled them. I was impressed with the trigger pull on the LCR I played with at the shop, but just like an alloy J-frame, recoil must be a complete bitch. The S&W Bodyguard 38 with the integrated laser seems interesting, very cheap compared with a 442 + lasergrips and a bit lighter.
The only revolver brands I recommend that are currently producing guns are Ruger and S&W. Charter Arms, Rossi, Taurus, or whatever other pot metal manufacturers there are out there are not worth even looking at, IMO. The QA/QC just isn’t there, and I’d rather not buy something that will start spraying bullet shavings at 500 rounds because the timing went to shit.
Whatever the choice, if she goes with a 38 revolver, I’d recommend a trigger job. And have her focus heavily on mastering the DA pull. Far too many people go to the range and shoot in SA because they want to make nice little groups on paper, but that really doesn’t help when there’s no time to cock the hammer after every shot. Any revolver I own for defense purposes I treat like a DAO, because that’s how I’m going to use it if I have to draw it in earnest.
But seriously, try to get her to buy an auto instead. A J-frame style 38 really is not a novice’s weapon; it is one of the hardest weapons to become proficient with. It’s very easy to develop a horrible flinch when you combine a heavy DA pull with the nasty recoil. It drives me nuts when I hear a gun shop employee pushing a J-frame on a woman buying her first gun, because they are just setting her up for failure. A S&W Shield or similar pistol would be orders of magnitude easier to learn on.