My opinion-S&W model 19. The Combat Magnum was the standard service revolver for decades for a reason. Several reasons, actually. Adjustable sights-for some this matters, for others not so much-great ergonomics, easy point-ability, awesome trigger in both single and double action, tough as a tank, and thousands upon thousands produced. If you get a pre 1982 manufacture, they have the pinned barrel and recessed cylinders. For some, this is a big deal. It’s not like they suck after that, but the craftsmanship just screams high quality. This is the only one on this list that I currently own, and I will never part with it.
The model 27 is also a great gun. A little heavier frame than the 19, but other wise pretty similar characteristics. Slightly less recoil on the 27 due to the frame, but the 19 points a little easier, in my opinion. Also, the 27 seems to be a little less plentiful than the 19. All that said, for me, if there was a 27 and a 19 side by side, I would pick up the 19. But I wouldnt feel bad about it if all I had available was a 27. It would be my second choice behind the 19.
As someone else mentioned, a model 13 is a good choice as well. 3 inch barrel with round butt is great for carry, but for your purposes as a nightstand gun those qualities are not as important. It is still a great gun though.
The 686 full underlug barrel is a drawback, at least for me. There is a ton of discussion out there on this. For some, myself included, the weight at the end of the barrel feels awkward. The other side of the discussion is that it reduces rise. For me, it doesn’t feel natural. This would actually be my last choice of those on your list.
The Ruger GP100 is a good gun, but the trigger on a Smith is much better. Smoother and a crisper break. Heavier than a comparable sized smith due to the casting process as has been discussed already. I like Rugers a lot, and I would’t turn down this gun, but it wouldn’t be my first choice. In fact, the Smith 19 or 27 would both be higher on my list than this one.